Category: Science Technology

Nov 05 2008

Bookmarks for November 3rd through November 5th

These are my links for November 3rd through November 5th:

A new clinical scoring system in Cystic Fibrosis: statistical tools for database analysis - a preliminary report -
Beautiful icons for your photo editing apps -
The New Yorker Magazine Interviews Cliff Bleszinski -
Don’t Quote Me (On When US$100=RMB100) -
¿Quiere convertirse en un profesional [...]

Nov 05 2008

A new clinical scoring system in Cystic Fibrosis: statistical tools for database analysis - a preliminary report

Background:
Cystic fibrosis is the most common fatal genetic disorder in the Caucasian population. Scoring systems for assessment of Cystic fibrosis disease severity have been used for almost 50 years, without being adapted to the milder phenotype of the disease in the 21st century. The aim of this current project is to develop a new scoring [...]

Nov 03 2008

Bookmarks for November 3rd from 16:39 to 22:22

These are my links for November 3rd from 16:39 to 22:22:

Mad Catz Fender Precision Bass Guitar - Xbox 360 Product Review -
State-by-State Polls Compared to Economic Indicators -
Obama: “I Love Rich People” -
What is ERROR PROOFING?? -
T. Boone Pickens: ‘Honey, I Shrunk the Charity’ -

Nov 03 2008

Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice

Background:
Familial Alzheimer’s disease-linked variants of presenilin (PSEN1 and PSEN2) contribute to the pathophysiology of disease by both gain-of-function and loss-of-function mechanisms. Deletions of PSEN1 and PSEN2 in the mouse forebrain result in a strong and progressive neurodegenerative phenotype which is characterized by both anatomical and behavioral changes.
Results:
To better understand the molecular changes associated with [...]

Nov 02 2008

Factors influencing the adoption of an innovation: An examination of the uptake of the Canadian Heart Health Kit (HHK)

Background:
There is an emerging knowledge base on the effectiveness of strategies to close the knowledge-practice gap. However, less is known about how attributes of an innovation, and other contextual and situational factors facilitate and impede an innovationas adoption. The Healthy Heart Kit (HHK) is a risk management and patient education resource for the prevention of [...]

Nov 01 2008

Abnormal spatial diffusion of Ca2+ in F508del-CFTR airway epithelial cells

Background:
In airway epithelial cells, calcium mobilization can be elicited by selective autocrine and/or paracrine activation of apical or basolateral membrane heterotrimeric G protein-coupled receptors linked to phospholipase C (PLC) stimulation, which generates inositol 1,4,5-trisphosphate (IP3) and 1,2-diacylglycerol (DAG) and induces Ca2+ release from endoplasmic reticulum (ER) stores.
Methods:

In the present study, we monitored the cytosolic [...]

Oct 31 2008

Personal and professional challenges in the management of deliberate self-poisoning patients in rural Sri Lanka: a qualitative study of rural hospital doctors’ experiences and perceptions

Background:
Deliberate self-poisoning is a major public heath issue in developing countries. In rural Sri Lanka deliberate self-poisoning is one of the leading causes of hospital death. The majority of patients with poisoning present to rural hospitals for initial treatment that are staffed by non-specialist and often relatively junior doctors.
The treatment of self-poisoning patients poses numerous [...]

Oct 29 2008

Assessing the unintended health impacts of road transport policies and interventions: translating research evidence for use in policy and practice

Background:
Transport and its links to health and health inequalities suggest that it is important to assess both the direct and unintended indirect health and related impacts of transport initiatives and policies. Health Impact Assessment (HIA) provides a framework to assess the possible health impacts of interventions such as transport. Policymakers and practitioners need [...]

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